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Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature

Anomalous left coronary artery from the pulmonary artery (ALCAPA) is considered a rare congenital heart disease where the take-off of the left coronary artery abnormally originates from the pulmonary artery instead of left aortic sinus. It is associated with a high mortality rate in the first year o...

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Autores principales: Bigdelu, Leila, Maadarani, Ossama, Azari, Ali, Heidari-Bakavoli, Ali, Bitar, Zouheir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348437/
https://www.ncbi.nlm.nih.gov/pubmed/37455696
http://dx.doi.org/10.12890/2023_003962
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author Bigdelu, Leila
Maadarani, Ossama
Azari, Ali
Heidari-Bakavoli, Ali
Bitar, Zouheir
author_facet Bigdelu, Leila
Maadarani, Ossama
Azari, Ali
Heidari-Bakavoli, Ali
Bitar, Zouheir
author_sort Bigdelu, Leila
collection PubMed
description Anomalous left coronary artery from the pulmonary artery (ALCAPA) is considered a rare congenital heart disease where the take-off of the left coronary artery abnormally originates from the pulmonary artery instead of left aortic sinus. It is associated with a high mortality rate in the first year of life and sudden death in adults if left untreated. We report an adult form of ALCAPA syndrome in a 20-year-old female who presented with anginal pain for the previous few months. Unfortunately, the patient was hesitant to have surgery at the time. LEARNING POINTS: The abnormal origin of the left coronary artery from the pulmonary artery (ALCAPA) is rare and potentially fatal coronary congenital disease, accounting for 0.5% of all congenital heart diseases; it is associated with poor outcomes if left untreated. ALCAPA is classified into infantile and adult forms. The prevalence of adult individuals with ALCAPA syndrome has significantly increased as a result of recent developments in non-invasive cardiac imaging. The prevalence of sudden mortality in childhood and the early stages of adulthood makes surgery the preferred treatment, and coronary reimplantation surgery is considered the surgical procedure of choice.
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spelling pubmed-103484372023-07-15 Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature Bigdelu, Leila Maadarani, Ossama Azari, Ali Heidari-Bakavoli, Ali Bitar, Zouheir Eur J Case Rep Intern Med Article Anomalous left coronary artery from the pulmonary artery (ALCAPA) is considered a rare congenital heart disease where the take-off of the left coronary artery abnormally originates from the pulmonary artery instead of left aortic sinus. It is associated with a high mortality rate in the first year of life and sudden death in adults if left untreated. We report an adult form of ALCAPA syndrome in a 20-year-old female who presented with anginal pain for the previous few months. Unfortunately, the patient was hesitant to have surgery at the time. LEARNING POINTS: The abnormal origin of the left coronary artery from the pulmonary artery (ALCAPA) is rare and potentially fatal coronary congenital disease, accounting for 0.5% of all congenital heart diseases; it is associated with poor outcomes if left untreated. ALCAPA is classified into infantile and adult forms. The prevalence of adult individuals with ALCAPA syndrome has significantly increased as a result of recent developments in non-invasive cardiac imaging. The prevalence of sudden mortality in childhood and the early stages of adulthood makes surgery the preferred treatment, and coronary reimplantation surgery is considered the surgical procedure of choice. SMC Media Srl 2023-06-26 /pmc/articles/PMC10348437/ /pubmed/37455696 http://dx.doi.org/10.12890/2023_003962 Text en © EFIM 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Article
Bigdelu, Leila
Maadarani, Ossama
Azari, Ali
Heidari-Bakavoli, Ali
Bitar, Zouheir
Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title_full Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title_fullStr Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title_full_unstemmed Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title_short Angina Pectoris as a Manifestation of ALCAPA Syndrome in a 20-Year-Old Female: A Case Report and Review of Literature
title_sort angina pectoris as a manifestation of alcapa syndrome in a 20-year-old female: a case report and review of literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348437/
https://www.ncbi.nlm.nih.gov/pubmed/37455696
http://dx.doi.org/10.12890/2023_003962
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