F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Muscle Uptake in Antiglutamic Acid Decarboxylase Antibody-positive Stiff-person Syndrome

Antiglutamic acid decarboxylase-65 (anti-GAD65) autoantibodies have been identified in variety of rare neurologic disorders most frequently in stiff-person syndrome (SPS), condition characterized by muscle rigidity and overlying painful spasms, typically affecting axial and limb musculature. In anti...

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Detalles Bibliográficos
Autores principales: Kamaleshwaran, Koramadai Karuppusamy, Ramkumar, Elumalai, Senthilkumar, Elumalai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348489/
https://www.ncbi.nlm.nih.gov/pubmed/37456188
http://dx.doi.org/10.4103/ijnm.ijnm_94_22
Descripción
Sumario:Antiglutamic acid decarboxylase-65 (anti-GAD65) autoantibodies have been identified in variety of rare neurologic disorders most frequently in stiff-person syndrome (SPS), condition characterized by muscle rigidity and overlying painful spasms, typically affecting axial and limb musculature. In anti-GAD65-related neurologic disorder, malignancy screening is often performed with (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). Here, we present an interesting image of 18FFDG PET/CT whole body showing muscle uptake and FDG brain showing thalamic hypometabolism in SPS.

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