Emergence of nociceptive functionality and opioid signaling in human induced pluripotent stem cell–derived sensory neurons

Induced pluripotent stem cells (iPSCs) have enabled the generation of various difficult-to-access cell types such as human nociceptors. A key challenge associated with human iPSC-derived nociceptors (hiPSCdNs) is their prolonged functional maturation. While numerous studies have addressed the expres...

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Detalles Bibliográficos
Autores principales: Röderer, Pascal, Belu, Andreea, Heidrich, Luzia, Siobal, Maike, Isensee, Jörg, Prolingheuer, Jonathan, Janocha, Elke, Valdor, Markus, Hagendorf, Silke, Bahrenberg, Gregor, Opitz, Thoralf, Segschneider, Michaela, Haupt, Simone, Nitzsche, Anja, Brüstle, Oliver, Hucho, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348637/
https://www.ncbi.nlm.nih.gov/pubmed/36727909
http://dx.doi.org/10.1097/j.pain.0000000000002860

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