Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice

Rift Valley fever virus (RVFV) is an emerging arbovirus found in Africa. While RVFV is pantropic and infects many cells and tissues, viral replication and necrosis within the liver play a critical role in mediating severe disease. The low-density lipoprotein receptor–related protein 1 (Lrp1) is a re...

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Detalles Bibliográficos
Autores principales: Schwarz, Madeline M., Ganaie, Safder S., Feng, Annie, Brown, Griffin, Yangdon, Tenzin, White, J. Michael, Hoehl, Ryan M., McMillen, Cynthia M., Rush, Rachael E., Connors, Kaleigh A., Cui, Xiaoxia, Leung, Daisy W., Egawa, Takeshi, Amarasinghe, Gaya K., Hartman, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348670/
https://www.ncbi.nlm.nih.gov/pubmed/37450601
http://dx.doi.org/10.1126/sciadv.adh2264

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