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Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation

During mammalian development, the left and right ventricles arise from early populations of cardiac progenitors known as the first and second heart fields, respectively. While these populations have been extensively studied in non-human model systems, their identification and study in vivo human tis...

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Detalles Bibliográficos
Autores principales: Galdos, Francisco X, Lee, Carissa, Lee, Soah, Paige, Sharon, Goodyer, William, Xu, Sidra, Samad, Tahmina, Escobar, Gabriela V, Darsha, Adrija, Beck, Aimee, Bak, Rasmus O, Porteus, Matthew H, Wu, Sean M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348749/
https://www.ncbi.nlm.nih.gov/pubmed/37284748
http://dx.doi.org/10.7554/eLife.80075

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