Cargando…
Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer’s disease
In this issue of the JCI, Wang and colleagues investigate the relationship between sleep disturbances, an environmental risk factor for Alzheimer’s disease (AD), and the apolipoprotein 4 (APOEε4) allele, a strong genetic risk factor for AD. The authors subjected an amyloid mouse model expressing hum...
Autores principales: | Sadleir, Katherine R., Vassar, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348763/ https://www.ncbi.nlm.nih.gov/pubmed/37463448 http://dx.doi.org/10.1172/JCI171838 |
Ejemplares similares
-
The Dichotomy of Alzheimer’s Disease Pathology: Amyloid-β and Tau
por: Ashford, J. Wesson
Publicado: (2019) -
Genetic Inhibition of Phosphorylation of the Translation Initiation Factor eIF2α Does Not Block Aβ-Dependent Elevation of BACE1 and APP Levels or Reduce Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
por: Sadleir, Katherine R., et al.
Publicado: (2014) -
ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease
por: Sadleir, Katherine R., et al.
Publicado: (2018) -
Should the ApoE genotype be a covariate for clinical trials in Alzheimer disease?
por: Farlow, Martin R
Publicado: (2010) -
Single-synapse analyses of Alzheimer’s disease implicate pathologic tau, DJ1, CD47, and ApoE
por: Phongpreecha, Thanaphong, et al.
Publicado: (2021)