1-Deoxynojirimycin promotes cardiac function and rescues mitochondrial cristae in mitochondrial hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most prominent cause of sudden cardiac death in young people. Due to heterogeneity in clinical manifestations, conventional HCM drugs have limitations for mitochondrial hypertrophic cardiomyopathy. Discovering more effective compounds would be of substantial...

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Detalles Bibliográficos
Autores principales: Zhuang, Qianqian, Guo, Fengfeng, Fu, Lei, Dong, Yufei, Xie, Shaofang, Ding, Xue, Hu, Shuangyi, Zhou, Xuanhao D., Jiang, Yangwei, Zhou, Hui, Qiu, Yue, Lei, Zhaoying, Li, Mengyao, Cai, Huajian, Fan, Mingjie, Sang, Lingjie, Fu, Yong, Zhang, Dong, Lin, Aifu, Li, Xu, Kunath, Tilo, Zhou, Ruhong, Liang, Ping, Liu, Zhong, Yan, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348775/
https://www.ncbi.nlm.nih.gov/pubmed/37200096
http://dx.doi.org/10.1172/JCI164660

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