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Counting pseudoalignments to novel splicing events

MOTIVATION: Alternative splicing (AS) of introns from pre-mRNA produces diverse sets of transcripts across cell types and tissues, but is also dysregulated in many diseases. Alignment-free computational methods have greatly accelerated the quantification of mRNA transcripts from short RNA-seq reads,...

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Detalles Bibliográficos
Autores principales: Borozan, Luka, Rojas Ringeling, Francisca, Kao, Shao-Yen, Nikonova, Elena, Monteagudo-Mesas, Pablo, Matijević, Domagoj, Spletter, Maria L, Canzar, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348833/
https://www.ncbi.nlm.nih.gov/pubmed/37432342
http://dx.doi.org/10.1093/bioinformatics/btad419