Cargando…

Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease

Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. A steep rise in AD incidents is observed in the elderly population in East-Asian countries. The disease progresses through several changes, including memory loss, behav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sundarrajan, Sudharsana, Venkatesan, Arthi, Kumar S, Udhaya, Gopikrishnan, Mohanraj, Tayubi, Iftikhar Aslam, Aditya, M, Siddaiah, Gowrishankar Bychapur, George Priya Doss, C., Zayed, Hatem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348954/ https://www.ncbi.nlm.nih.gov/pubmed/37162726 http://dx.doi.org/10.1007/s11011-023-01221-7

Ejemplares similares

Unraveling the Dysbiosis of Vaginal Microbiome to Understand Cervical Cancer Disease Etiology—An Explainable AI Approach
por: Sekaran, Karthik, et al.
Publicado: (2023)

Evaluating Andrographolide as a Potent Inhibitor of NS3-4A Protease and Its Drug-Resistant Mutants Using In Silico Approaches
por: Chandramohan, Vivek, et al.
Publicado: (2015)

Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer
por: Kumar, S. Udhaya, et al.
Publicado: (2019)

Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2
por: Kumar D, Thirumal, et al.
Publicado: (2021)

Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer
por: Gopikrishnan, Mohanraj, et al.
Publicado: (2023)

Comorbidities of Psoriasis - Exploring the Links by Network Approach
por: Sundarrajan, Sudharsana, et al.
Publicado: (2016)

Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma
por: Dey, Hrituraj, et al.
Publicado: (2023)

Biomineralization associated alkaline phosphatase as a potential marker of bone metastasis in the patients with invasive breast cancer
por: Tayubi, Iftikhar Aslam, et al.
Publicado: (2022)

Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach
por: Udhaya Kumar, S., et al.
Publicado: (2020)

Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients – A Bioinformatics Approach
por: Udhaya Kumar, S., et al.
Publicado: (2020)

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia
por: Ibrahim, Ali Zaki, et al.
Publicado: (2020)

A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing
por: Kumar, S. Udhaya, et al.
Publicado: (2021)

In silico analysis of detrimental mutation in EPHB2 gene causing Alzheimer’s disease
por: Tayubi, Iftikhar Aslam, et al.
Publicado: (2014)

Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity
por: S., Udhaya Kumar, et al.
Publicado: (2020)

Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach
por: S., Udhaya Kumar, et al.
Publicado: (2020)

Bioinformatics classification of mutations in patients with Mucopolysaccharidosis IIIA
por: Tanwar, Himani, et al.
Publicado: (2019)

Bioinformatics investigation on blood-based gene expressions of Alzheimer's disease revealed ORAI2 gene biomarker susceptibility: An explainable artificial intelligence-based approach
por: Sekaran, Karthik, et al.
Publicado: (2023)

Towards the early detection of ductal carcinoma (a common type of breast cancer) using biomarkers linked to the PPAR(γ) signaling pathway
por: Sultan, Ghazala, et al.
Publicado: (2019)

Influence of PCOS in Obese vs. Non-Obese women from Mesenchymal Progenitors Stem Cells and Other Endometrial Cells: An in silico biomarker discovery
por: Desai, Ashvini, et al.
Publicado: (2017)

Kerala, India's Front Runner in Novel Coronavirus Disease (COVID-19)
por: Udhaya Kumar, S., et al.
Publicado: (2020)

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
por: P., Sneha, et al.
Publicado: (2017)

The Rise and Impact of COVID-19 in India
por: Kumar, S. Udhaya, et al.
Publicado: (2020)

Drug formulation studies on regulation of BCL-2 family for treatment of autism
por: Tayubi, Iftikhar A, et al.
Publicado: (2014)

Decoding Conformational Imprint of Convoluted Molecular Interactions Between Prenylflavonoids and Aggregated Amyloid-Beta42 Peptide Causing Alzheimer’s Disease
por: Srinivasan, E., et al.
Publicado: (2021)

Airway and Oral microbiome profiling of SARS-CoV-2 infected asthma and non-asthma cases revealing alterations–A pulmonary microbial investigation
por: Sekaran, Karthik, et al.
Publicado: (2023)

Pregnancy Outcomes in Late Onset Pompe Disease
por: Goker-Alpan, Ozlem, et al.
Publicado: (2020)

Genetic characterization of Chikungunya virus 2009 isolates from South India
por: Sarangan, Gopalsamy, et al.
Publicado: (2018)

Identification of marker genes in Alzheimer's disease using a machine-learning model
por: Madar, Inamul Hasan, et al.
Publicado: (2021)

Shock and dyselectrolytemia in a neonate with late-onset COVID-19 infection
por: Kallimath, Aditya, et al.
Publicado: (2021)

Late, late-onset infections in the nursery.
por: Baltimore, R. S.
Publicado: (1988)

Corrigendum: Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World
por: Doss, C. George Priya, et al.
Publicado: (2017)

Genetic Epidemiology of Glucose-6-Phosphate Dehydrogenase Deficiency in the Arab World
por: Doss, C. George Priya, et al.
Publicado: (2016)

Exome Sequencing as a Diagnostic Tool for Pediatric-Onset Ataxia
por: Sawyer, Sarah L, et al.
Publicado: (2014)

Exome Sequencing of 5 Families with Severe Early-Onset Periodontitis
por: Richter, G.M., et al.
Publicado: (2021)

Utility of Exome Sequencing for Diagnosis in Unexplained Pediatric-Onset Epilepsy
por: Koh, Hyun Yong, et al.
Publicado: (2023)

The first Vietnamese patient who presented late onset of pantothenate kinase-associated neurodegeneration diagnosed by whole exome sequencing: A case report
por: Tran, Van Khanh, et al.
Publicado: (2023)

Late-onset hypogonadism
por: Dudek, Piotr, et al.
Publicado: (2017)

Late-Onset Dystrophinopathy
por: Singh, Ranjan K
Publicado: (2021)

Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery
por: Rachid, Mohamad, et al.
Publicado: (2017)

LATE ONSET PSYCHOSIS AND VERY LATE ONSET PSYCHOSIS: WHAT ARE THE POSSIBLE ETHIOLOGIES?
por: Ramos, A. C., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cu030ph50rov7h98ats8o8ps9b