Endothelial ILK induces cardioprotection by preventing coronary microvascular dysfunction and endothelial-to-mesenchymal transition

Endothelial dysfunction is an early event in coronary microvascular disease. Integrin-linked kinase (ILK) prevents endothelial nitric oxide synthase (eNOS) uncoupling and, thus, endothelial dysfunction. However, the specific role of endothelial ILK in cardiac function remains to be fully elucidated....

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Detalles Bibliográficos
Autores principales: Reventun, P., Sánchez-Esteban, S., Cook-Calvete, A., Delgado-Marín, M., Roza, C., Jorquera-Ortega, S., Hernandez, I., Tesoro, L., Botana, L., Zamorano, J. L., Zaragoza, C., Saura, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348984/
https://www.ncbi.nlm.nih.gov/pubmed/37452166
http://dx.doi.org/10.1007/s00395-023-00997-0

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