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Polymeric epitope-based vaccine induces protective immunity against group A Streptococcus

Group A Streptococcus (Strep A) is a life-threatening human pathogen with no licensed vaccine. Here, we used a biopolymer particle (BP) approach to display repeats of Strep A vaccine candidate peptides p*17 and K4S2 derived from M and non-M protein, respectively. BPs densely displaying both peptides...

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Detalles Bibliográficos
Autores principales:	Chen, Shuxiong, Ozberk, Victoria, Sam, Gayathri, Gonzaga, Zennia Jean C., Calcutt, Ainslie, Pandey, Manisha, Good, Michael F., Rehm, Bernd H. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349049/ https://www.ncbi.nlm.nih.gov/pubmed/37452052 http://dx.doi.org/10.1038/s41541-023-00695-x

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