Cargando…
FOXM1 is critical for the fitness recovery of chromosomally unstable cells
Tumor progression and evolution are frequently associated with chromosomal instability (CIN). Tumor cells often express high levels of the mitotic checkpoint protein MAD2, leading to mitotic arrest and cell death. However, some tumor cells are capable of exiting mitosis and consequently increasing C...
Autores principales: | Pan, Fan, Chocarro, Sara, Ramos, Maria, Chen, Yuanyuan, Alonso de la Vega, Alicia, Somogyi, Kalman, Sotillo, Rocio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349069/ https://www.ncbi.nlm.nih.gov/pubmed/37452072 http://dx.doi.org/10.1038/s41419-023-05946-2 |
Ejemplares similares
-
Acquisition of chromosome instability is a mechanism to evade oncogene addiction
por: Salgueiro, Lorena, et al.
Publicado: (2020) -
Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment
por: Alikhanyan, Kristina, et al.
Publicado: (2021) -
Acute expression of human APOBEC3B in mice results in RNA editing and lethality
por: Alonso de la Vega, Alicia, et al.
Publicado: (2023) -
Plk1 overexpression induces chromosomal instability and suppresses tumor development
por: de Cárcer, Guillermo, et al.
Publicado: (2018) -
Club cells employ regeneration mechanisms during lung tumorigenesis
por: Chen, Yuanyuan, et al.
Publicado: (2022)