Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement

Malaria parasite lacks canonical pathways for amino acid biosynthesis and depends primarily on hemoglobin degradation and extracellular resources for amino acids. Interestingly, a putative gene for glutamine synthetase (GS) is retained despite glutamine being an abundant amino acid in human and mosq...

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Detalles Bibliográficos
Autores principales: Ghosh, Sourav, Kundu, Rajib, Chandana, Manjunatha, Das, Rahul, Anand, Aditya, Beura, Subhashree, Bobde, Ruchir Chandrakant, Jain, Vishal, Prabhu, Sowmya Ramakant, Behera, Prativa Kumari, Mohanty, Akshaya Kumar, Chakrapani, Mahabala, Satyamoorthy, Kapaettu, Suryawanshi, Amol Ratnakar, Dixit, Anshuman, Padmanaban, Govindarajan, Nagaraj, Viswanathan Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349072/
https://www.ncbi.nlm.nih.gov/pubmed/37452051
http://dx.doi.org/10.1038/s41467-023-39670-4

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