Restricting epigenetic activity promotes the reprogramming of transformed cells to pluripotency in a line-specific manner

Somatic cell reprogramming and oncogenic transformation share surprisingly similar features, yet transformed cells are resistant to reprogramming. Epigenetic barriers must block transformed cells from reprogramming, but the nature of those barriers is unclear. In this study, we generated a systemati...

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Detalles Bibliográficos
Autores principales: Fu, Xiuling, Zhuang, Qiang, Babarinde, Isaac A., Shi, Liyang, Ma, Gang, Hu, Haoqing, Li, Yuhao, Chen, Jiao, Xiao, Zhen, Deng, Boping, Sun, Li, Jauch, Ralf, Hutchins, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349098/
https://www.ncbi.nlm.nih.gov/pubmed/37452056
http://dx.doi.org/10.1038/s41420-023-01533-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349098/
https://www.ncbi.nlm.nih.gov/pubmed/37452056
http://dx.doi.org/10.1038/s41420-023-01533-8

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