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Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes

Obesity-induced adipose tissue dysfunction can cause low-grade inflammation and downstream obesity comorbidities. Although preadipocytes may contribute to this pro-inflammatory environment, the underlying mechanisms are unclear. We used human primary preadipocytes from body mass index (BMI) -discord...

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Detalles Bibliográficos
Autores principales:	Garske, Kristina M., Kar, Asha, Comenho, Caroline, Balliu, Brunilda, Pan, David Z., Bhagat, Yash V., Rosenberg, Gregory, Koka, Amogha, Das, Sankha Subhra, Miao, Zong, Sinsheimer, Janet S., Kaprio, Jaakko, Pietiläinen, Kirsi H., Pajukanta, Päivi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349101/ https://www.ncbi.nlm.nih.gov/pubmed/37452040 http://dx.doi.org/10.1038/s41467-023-39919-y

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