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Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins

Chemokines are key regulators of leukocyte trafficking and attractive targets for anti-inflammatory therapy. Evasins are chemokine-binding proteins from tick saliva, whose application as anti-inflammatory therapeutics will require manipulation of their chemokine target selectivity. Here we describe...

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Detalles Bibliográficos
Autores principales:	Devkota, Shankar Raj, Aryal, Pramod, Pokhrel, Rina, Jiao, Wanting, Perry, Andrew, Panjikar, Santosh, Payne, Richard J., Wilce, Matthew C. J., Bhusal, Ram Prasad, Stone, Martin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349104/ https://www.ncbi.nlm.nih.gov/pubmed/37452046 http://dx.doi.org/10.1038/s41467-023-39879-3

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