Cargando…

High-throughput functional screen identifies YWHAZ as a key regulator of pancreatic cancer metastasis

Pancreatic cancer is a leading cause of cancer death due to its early metastasis and limited response to the current therapies. Metastasis is a complicated multistep process, which is determined by complex genetic alterations. Despite the identification of many metastasis-related genes, distinguishi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Fang, Jiang, Yunpeng, Chang, Lin, Du, Hongzhen, Chang, De, Pan, Chunxiao, Huang, Xiaozheng, Yu, Donglin, Zhang, Mi, Fan, Yongna, Bian, Xiaocui, Li, Kailong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349114/ https://www.ncbi.nlm.nih.gov/pubmed/37452033 http://dx.doi.org/10.1038/s41419-023-05951-5

Ejemplares similares

A controlled random gene perturbation method identifies ARPC1B gene as a key regulator of cancer metastasis
por: Chang, De, et al.
Publicado: (2022)

miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival
por: Chen, Ming, et al.
Publicado: (2016)

Expression of ywhaz and gene regulation network in hepatocellular carcinoma
por: Lin, Yi, et al.
Publicado: (2020)

The role of YWHAZ in cancer: A maze of opportunities and challenges
por: Gan, Yun, et al.
Publicado: (2020)

A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway
por: Popov, Ivan K., et al.
Publicado: (2019)

MiR-1-3p Suppresses Colorectal Cancer Cell Proliferation and Metastasis by Inhibiting YWHAZ-Mediated Epithelial–Mesenchymal Transition
por: Du, Guanghong, et al.
Publicado: (2021)

Transcriptional Regulation of YWHAZ, the Gene Encoding 14-3-3ζ
por: Kasinski, Andrea, et al.
Publicado: (2014)

YWHAZ interacts with DAAM1 to promote cell migration in breast cancer
por: Mei, Jie, et al.
Publicado: (2021)

The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma
por: Zhao, Juan-Feng, et al.
Publicado: (2018)

Overexpression of YWHAZ relates to tumor cell proliferation and malignant outcome of gastric carcinoma
por: Nishimura, Y, et al.
Publicado: (2013)

Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
por: Wang, Wenrui, et al.
Publicado: (2017)

The expression of YWHAZ and NDRG1 predicts aggressive outcome in human prostate cancer
por: Lage-Vickers, Sofia, et al.
Publicado: (2021)

MiRNA-1225 Inhibits Osteosarcoma Tumor Growth and Progression by Targeting YWHAZ
por: Gong, Yubao, et al.
Publicado: (2021)

YWHAZ variation causes intellectual disability and global developmental delay with brain malformation
por: Wan, Rui-Ping, et al.
Publicado: (2022)

Circ‐SERPINE2 promotes the development of gastric carcinoma by sponging miR‐375 and modulating YWHAZ
por: Liu, Jianing, et al.
Publicado: (2019)

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer
por: Li, Yang, et al.
Publicado: (2010)

Involvement of miR-30c in resistance to doxorubicin by regulating YWHAZ in breast cancer cells
por: Fang, Y., et al.
Publicado: (2014)

MiRNA-802 suppresses proliferation and migration of epithelial ovarian cancer cells by targeting YWHAZ
por: Yang, Bo, et al.
Publicado: (2019)

YY1-modulated long non-coding RNA SNHG12 promotes gastric cancer metastasis by activating the miR-218-5p/YWHAZ axis
por: Zhang, Tianqi, et al.
Publicado: (2021)

TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation
por: Franko, Nina, et al.
Publicado: (2022)

Lnc524369 promotes hepatocellular carcinoma progression and predicts poor survival by activating YWHAZ-RAF1 signaling
por: Zheng, Wei, et al.
Publicado: (2022)

G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer
por: Zhao, Junjie, et al.
Publicado: (2020)

YWHAZ and TBP are potential reference gene candidates for qPCR analysis of response to radiation therapy in colorectal cancer
por: Kim, Shin, et al.
Publicado: (2023)

Analyzing the Impact of Diesel Exhaust Particles on Lung Fibrosis Using Dual PCR Array and Proteomics: YWHAZ Signaling
por: Kim, Byeong-Gon, et al.
Publicado: (2023)

Hsa_circ_0002496 promotes the growth, angiogenesis, and stemness of breast cancer cells via miR‐433‐3p/YWHAZ cascade
por: Yang, Chao, et al.
Publicado: (2023)

MicroRNA-375 Suppresses the Tumor Aggressive Phenotypes of Clear Cell Renal Cell Carcinomas through Regulating YWHAZ
por: Zhang, Xiang, et al.
Publicado: (2018)

YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo‐/radio‐resistance by suppressing caspase‐mediated apoptosis
por: Yu, Chia‐Cheng, et al.
Publicado: (2019)

Inhibition of miR-22 promotes differentiation of osteoblasts and improves bone formation via the YWHAZ pathway in experimental mice
por: Yin, Peiyi, et al.
Publicado: (2019)

ITGB1 Drives Hepatocellular Carcinoma Progression by Modulating Cell Cycle Process Through PXN/YWHAZ/AKT Pathways
por: Xie, Jinghe, et al.
Publicado: (2021)

Coexistence of YWHAZ amplification predicts better prognosis in muscle-invasive bladder cancer with CDKN2A or TP53 loss
por: Liu, Shenghua, et al.
Publicado: (2016)

Expression of PD-L1 and YWHAZ in Patients with Diffuse Large B Cell Lymphoma: A Possible Association with the Prognosis of Lymphoma
por: Yan, Shufang, et al.
Publicado: (2022)

gga-miR-451 Negatively Regulates Mycoplasma gallisepticum (HS Strain)-Induced Inflammatory Cytokine Production via Targeting YWHAZ
por: Zhao, Yabo, et al.
Publicado: (2018)

PPIA, HPRT1, and YWHAZ Genes Are Suitable for Normalization of mRNA Expression in Long-Term Expanded Human Mesenchymal Stem Cells
por: Jeon, Ryoung-Hoon, et al.
Publicado: (2019)

Circular RNA circNHSL1 Contributes to Gastric Cancer Progression Through the miR-149-5p/YWHAZ Axis
por: Hui, Chunying, et al.
Publicado: (2020)

Paclitaxel Suppresses Hepatocellular Carcinoma Tumorigenesis Through Regulating Circ-BIRC6/miR-877-5p/YWHAZ Axis
por: Liu, Yi, et al.
Publicado: (2020)

PPIA, HPRT1, and YWHAZ are suitable reference genes for quantitative polymerase chain reaction assay of the hypothalamic–pituitary–gonadal axis in sows
por: Kim, Hwan-Deuk, et al.
Publicado: (2022)

High throughput analysis to identify key gene molecules that inhibit adipogenic differentiation and promote osteogenic differentiation of human mesenchymal stem cells
por: Peng, Wu-Xun, et al.
Publicado: (2019)

Hub genes and key pathways of non-small lung cancer identified using bioinformatics
por: Tang, Qing, et al.
Publicado: (2018)

Identifying key factors for the effectiveness of pancreatic cancer screening: A model‐based analysis
por: Koopmann, Brechtje D. M., et al.
Publicado: (2021)

An evidence-based knowledgebase of metastasis suppressors to identify key pathways relevant to cancer metastasis
por: Zhao, Min, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_oltcnb7hmgd8rq7et1jg99n9i6