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Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling

Objective This study set out to examine the results of microneedling (MN) with and without injectable platelet-rich fibrin (i-PRF) in treating individuals with thin periodontal phenotypes, specifically focusing on the effects on gingival thickness (GT) and keratinized tissue width (KTW). Materials a...

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Autores principales: Adhikary, Rajnandini, Mohan, Prerna, Wadhawan, Amit, Tyagi, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349171/
https://www.ncbi.nlm.nih.gov/pubmed/37456469
http://dx.doi.org/10.7759/cureus.40435
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author Adhikary, Rajnandini
Mohan, Prerna
Wadhawan, Amit
Tyagi, Prashant
author_facet Adhikary, Rajnandini
Mohan, Prerna
Wadhawan, Amit
Tyagi, Prashant
author_sort Adhikary, Rajnandini
collection PubMed
description Objective This study set out to examine the results of microneedling (MN) with and without injectable platelet-rich fibrin (i-PRF) in treating individuals with thin periodontal phenotypes, specifically focusing on the effects on gingival thickness (GT) and keratinized tissue width (KTW). Materials and methods This was a split-mouth study involving 32 healthy patients with 64 sites having thin phenotypes classified into two groups. On the one side, i-PRF was injected (Group A), while on the other side (Group B), MN along with i-PRF was used at intervals of 10 days for a month. GT and KTW were measured at baseline, three months, and six months. The parameters were compared intra and intergroup-wise at baseline, three months, and six months using the IBM SPSS Statistics software version 24 (IBM Corp., Armonk, NY) and the chi-square test. Results The findings revealed that when comparing Group A, which received just i-PRF, to Group B, which had i-PRF in conjunction with MN, there was a statistically significant increase in GT in Group B. Conclusions This is a novel method in that it does not need surgical innervations to expand the gingiva in breadth or thickness. Although MN's neoangiogenesis impact contributed to thicker gingiva, i-PRF showed a greater capacity for the release of several growth factors.
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spelling pubmed-103491712023-07-16 Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling Adhikary, Rajnandini Mohan, Prerna Wadhawan, Amit Tyagi, Prashant Cureus Dentistry Objective This study set out to examine the results of microneedling (MN) with and without injectable platelet-rich fibrin (i-PRF) in treating individuals with thin periodontal phenotypes, specifically focusing on the effects on gingival thickness (GT) and keratinized tissue width (KTW). Materials and methods This was a split-mouth study involving 32 healthy patients with 64 sites having thin phenotypes classified into two groups. On the one side, i-PRF was injected (Group A), while on the other side (Group B), MN along with i-PRF was used at intervals of 10 days for a month. GT and KTW were measured at baseline, three months, and six months. The parameters were compared intra and intergroup-wise at baseline, three months, and six months using the IBM SPSS Statistics software version 24 (IBM Corp., Armonk, NY) and the chi-square test. Results The findings revealed that when comparing Group A, which received just i-PRF, to Group B, which had i-PRF in conjunction with MN, there was a statistically significant increase in GT in Group B. Conclusions This is a novel method in that it does not need surgical innervations to expand the gingiva in breadth or thickness. Although MN's neoangiogenesis impact contributed to thicker gingiva, i-PRF showed a greater capacity for the release of several growth factors. Cureus 2023-06-14 /pmc/articles/PMC10349171/ /pubmed/37456469 http://dx.doi.org/10.7759/cureus.40435 Text en Copyright © 2023, Adhikary et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dentistry
Adhikary, Rajnandini
Mohan, Prerna
Wadhawan, Amit
Tyagi, Prashant
Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title_full Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title_fullStr Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title_full_unstemmed Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title_short Gingival Augmentation in the Thin Phenotype Using Injectable Platelet-Rich Fibrin and Microneedling
title_sort gingival augmentation in the thin phenotype using injectable platelet-rich fibrin and microneedling
topic Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349171/
https://www.ncbi.nlm.nih.gov/pubmed/37456469
http://dx.doi.org/10.7759/cureus.40435
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