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Novel aspect of neprilysin in kidney fibrosis via ACSL4‐mediated ferroptosis of tubular epithelial cells

Although inhibition of neprilysin (NEP) might be a therapeutic strategy with the potential to improve the outcome of chronic kidney disease (CKD), the versatile function of NEP with its mechanism remains obscure in kidney fibrosis. In the study, we found that NEP was abnormally increased in tubular...

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Detalles Bibliográficos
Autores principales: Lai, Weijing, Huang, Rongshuang, Wang, Bo, Shi, Min, Guo, Fan, Li, Lingzhi, Ren, Qian, Tao, Sibei, Fu, Ping, Ma, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349188/
https://www.ncbi.nlm.nih.gov/pubmed/37457659
http://dx.doi.org/10.1002/mco2.330