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A novel hybrid bioprocess strategy addressing key challenges of advanced biomanufacturing

Monoclonal antibodies (mAb) are commonly manufactured by either discontinuous operations like fed-batch (FB) or continuous processes such as steady-state perfusion. Both process types comprise opposing advantages and disadvantages in areas such as plant utilization, feasible cell densities, media co...

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Detalles Bibliográficos
Autores principales: Reger, Lucas Nik, Saballus, Martin, Kappes, Annika, Kampmann, Markus, Wijffels, Rene H., Martens, Dirk E., Niemann, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349264/
https://www.ncbi.nlm.nih.gov/pubmed/37456731
http://dx.doi.org/10.3389/fbioe.2023.1211410

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