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A tumor mutational burden-derived immune computational framework selects sensitive immunotherapy/chemotherapy for lung adenocarcinoma populations with different prognoses

BACKGROUND: Lung adenocarcinoma (LUAD) kills millions of people every year. Recently, FDA and researchers proved the significance of high tumor mutational burden (TMB) in treating solid tumors. But no scholar has constructed a TMB-derived computing framework to select sensitive immunotherapy/chemoth...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenlong, Wei, Chuzhong, Huang, Fengyu, Huang, Wencheng, Xu, Xiaoxin, Zhu, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349266/ https://www.ncbi.nlm.nih.gov/pubmed/37456238 http://dx.doi.org/10.3389/fonc.2023.1104137

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