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EPD1504: a novel μ-opioid receptor partial agonist attenuates obsessive–compulsive disorder (OCD)-like behaviors

Low doses of μ-opioid receptor (MOR) agonists rapidly ameliorate symptoms in treatment-resistant obsessive–compulsive disorder (OCD) patients (10–50% of OCD patients). However, the utility of MOR agonists is limited by their safety liabilities. We developed a novel MOR partial agonist (EPD1540) that...

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Detalles Bibliográficos
Autores principales:	Youngblood, Beth, Medina, Julio C., Gehlert, Donald R., Schwartz, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349350/ https://www.ncbi.nlm.nih.gov/pubmed/37457777 http://dx.doi.org/10.3389/fpsyt.2023.1170541

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