COVID-19-Related Rhino-Orbital-Cerebral Mucormycosis With Angioinvasion: A Lethal Sequelae

A middle-aged man with multiple comorbidities including uncontrolled diabetes mellitus presented with shortness of breath and lethargy for six days. He was treated for COVID-19 pneumonia, requiring high cumulative steroid therapy. After 15 days of treatment, he developed right orbital apex syndrome...

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Detalles Bibliográficos
Autores principales: Redzuwan, Nur Syazwani, Barr Kumarakulasinghe, Andrea Lillianne, W Md Kasim, Wan Mariny, Mohd Khialdin, Safinaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349690/
https://www.ncbi.nlm.nih.gov/pubmed/37461781
http://dx.doi.org/10.7759/cureus.40483
Descripción
Sumario:A middle-aged man with multiple comorbidities including uncontrolled diabetes mellitus presented with shortness of breath and lethargy for six days. He was treated for COVID-19 pneumonia, requiring high cumulative steroid therapy. After 15 days of treatment, he developed right orbital apex syndrome with central retinal artery occlusion secondary to invasive mucormycosis. The infection progressed rapidly despite aggressive medical treatment, systemic anti-fungal therapy along with local transcutaneous retrobulbar amphotericin B injection. We report our battle in fighting this vicious disease. Judicious use of immunomodulators in COVID-19 treatment and close monitoring is crucial, especially in high-risk patients.

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