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Mechanistic investigation of a D to N mutation in DAHP synthase that dictates carbon flux into the shikimate pathway in yeast

3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) is a key enzyme in the shikimate pathway for the biosynthesis of aromatic compounds. (L)-Phe and (L)-Tyr bind to the two main DAHPS isoforms and inhibit their enzyme activities, respectively. Synthetic biologists aim to relieve such inhibi...

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Detalles Bibliográficos
Autores principales:	Liu, Huayi, Xiao, Qingjie, Wu, Xinxin, Ma, He, Li, Jian, Guo, Xufan, Liu, Zhenyu, Zhang, Yan, Luo, Yunzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349828/ https://www.ncbi.nlm.nih.gov/pubmed/37454208 http://dx.doi.org/10.1038/s42004-023-00946-x

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