Flt1 produced by lung endothelial cells impairs ATII cell transdifferentiation and repair in pulmonary fibrosis

Pulmonary fibrosis is a devastating disease, in which fibrotic tissue progressively replaces lung alveolar structure, resulting in chronic respiratory failure. Alveolar type II cells act as epithelial stem cells, being able to transdifferentiate into alveolar type I cells, which mediate gas exchange...

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Detalles Bibliográficos
Autores principales: Volpe, Maria Concetta, Ciucci, Giulio, Zandomenego, Giulia, Vuerich, Roman, Ring, Nadja Anneliese Ruth, Vodret, Simone, Salton, Francesco, Marchesan, Pietro, Braga, Luca, Marcuzzo, Thomas, Bussani, Rossana, Colliva, Andrea, Piazza, Silvano, Confalonieri, Marco, Zacchigna, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349845/
https://www.ncbi.nlm.nih.gov/pubmed/37454154
http://dx.doi.org/10.1038/s41419-023-05962-2

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