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PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling

PLAGL2 is upregulated in various tumors, including bladder cancer (BCa). However, the mechanisms underlying the tumorigenic effects of PLAGL2 in BCa remain unclear. In our study, we proved that PLAGL2 was overexpressed in BCa tissues and correlated with decreased survival. Functionally, PLAGL2 defic...

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Detalles Bibliográficos
Autores principales: Chen, Hualin, Yang, Wenjie, Li, Yingjie, Ji, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349853/
https://www.ncbi.nlm.nih.gov/pubmed/37454211
http://dx.doi.org/10.1038/s41419-023-05970-2

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