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TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

Breast cancer is the most frequently diagnosed cancer in women. The most common subtype is luminal breast cancer, which is typically driven by the estrogen receptor α (ER), a transcription factor (TF) that activates many genes required for proliferation. Multiple effective therapies target this path...

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Detalles Bibliográficos
Autores principales:	Scott, Thomas G., Sathyan, Kizhakke Mattada, Gioeli, Daniel, Guertin, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349936/ https://www.ncbi.nlm.nih.gov/pubmed/37461612 http://dx.doi.org/10.1101/2023.07.03.547524

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