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TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells
Breast cancer is the most frequently diagnosed cancer in women. The most common subtype is luminal breast cancer, which is typically driven by the estrogen receptor α (ER), a transcription factor (TF) that activates many genes required for proliferation. Multiple effective therapies target this path...
Autores principales: | Scott, Thomas G., Sathyan, Kizhakke Mattada, Gioeli, Daniel, Guertin, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349936/ https://www.ncbi.nlm.nih.gov/pubmed/37461612 http://dx.doi.org/10.1101/2023.07.03.547524 |
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