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Synaptophysin Chaperones the Assembly of 12 SNAREpins under each Ready-Release Vesicle
The synaptic vesicle protein Synaptophysin has long been known to form a complex with the v-SNARE VAMP, but a more specific molecular function or mechanism of action in exocytosis has been lacking because gene knockouts have minimal effects. Utilizing fully-defined reconstitution and single-molecule...
Autores principales: | Bera, Manindra, Radhakrishnan, Abhijith, Coleman, Jeff, Sundaram, Ramalingam Venkat Kalyana, Ramakrishnan, Sathish, Pincet, Frederic, Rothman, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349951/ https://www.ncbi.nlm.nih.gov/pubmed/37461465 http://dx.doi.org/10.1101/2023.07.05.547834 |
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