Synaptophysin Chaperones the Assembly of 12 SNAREpins under each Ready-Release Vesicle

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The synaptic vesicle protein Synaptophysin has long been known to form a complex with the v-SNARE VAMP, but a more specific molecular function or mechanism of action in exocytosis has been lacking because gene knockouts have minimal effects. Utilizing fully-defined reconstitution and single-molecule...

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Detalles Bibliográficos
Autores principales: Bera, Manindra, Radhakrishnan, Abhijith, Coleman, Jeff, Sundaram, Ramalingam Venkat Kalyana, Ramakrishnan, Sathish, Pincet, Frederic, Rothman, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349951/
https://www.ncbi.nlm.nih.gov/pubmed/37461465
http://dx.doi.org/10.1101/2023.07.05.547834
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