Replication Protein A1 is essential for DNA damage repair during mammalian oogenesis

Persistence of unrepaired DNA damage in oocytes is detrimental and may cause genetic aberrations, miscarriage, and infertility. RPA, an ssDNA-binding complex, is essential for various DNA-related processes. Here we report that RPA plays a novel role in DNA damage repair during postnatal oocyte devel...

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Detalles Bibliográficos
Autores principales: Miao, Xiaosu, Guo, Rui, Williams, Andrea, Lee, Catherine, Ma, Jun, Wang, P. Jeremy, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349974/
https://www.ncbi.nlm.nih.gov/pubmed/37461444
http://dx.doi.org/10.1101/2023.07.04.547725

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