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Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis

BACKGROUND: Machine learning (ML) has emerged as a vital asset for researchers to analyze and extract valuable information from complex datasets. However, developing an effective and robust ML pipeline can present a real challenge, demanding considerable time and effort, thereby impeding research pr...

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Autores principales: Akshay, Akshay, Katoch, Mitali, Shekarchizadeh, Navid, Abedi, Masoud, Sharma, Ankush, Burkhard, Fiona C., Adam, Rosalyn M., Monastyrskaya, Katia, Gheinani, Ali Hashemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349995/
https://www.ncbi.nlm.nih.gov/pubmed/37461685
http://dx.doi.org/10.1101/2023.07.04.546825
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author Akshay, Akshay
Katoch, Mitali
Shekarchizadeh, Navid
Abedi, Masoud
Sharma, Ankush
Burkhard, Fiona C.
Adam, Rosalyn M.
Monastyrskaya, Katia
Gheinani, Ali Hashemi
author_facet Akshay, Akshay
Katoch, Mitali
Shekarchizadeh, Navid
Abedi, Masoud
Sharma, Ankush
Burkhard, Fiona C.
Adam, Rosalyn M.
Monastyrskaya, Katia
Gheinani, Ali Hashemi
author_sort Akshay, Akshay
collection PubMed
description BACKGROUND: Machine learning (ML) has emerged as a vital asset for researchers to analyze and extract valuable information from complex datasets. However, developing an effective and robust ML pipeline can present a real challenge, demanding considerable time and effort, thereby impeding research progress. Existing tools in this landscape require a profound understanding of ML principles and programming skills. Furthermore, users are required to engage in the comprehensive configuration of their ML pipeline to obtain optimal performance. RESULTS: To address these challenges, we have developed a novel tool called Machine Learning Made Easy (MLme) that streamlines the use of ML in research, specifically focusing on classification problems at present. By integrating four essential functionalities, namely Data Exploration, AutoML, CustomML, and Visualization, MLme fulfills the diverse requirements of researchers while eliminating the need for extensive coding efforts. To demonstrate the applicability of MLme, we conducted rigorous testing on six distinct datasets, each presenting unique characteristics and challenges. Our results consistently showed promising performance across different datasets, reaffirming the versatility and effectiveness of the tool. Additionally, by utilizing MLme’s feature selection functionality, we successfully identified significant markers for CD8+ naive (BACH2), CD16+ (CD16), and CD14+ (VCAN) cell populations. CONCLUSION: MLme serves as a valuable resource for leveraging machine learning (ML) to facilitate insightful data analysis and enhance research outcomes, while alleviating concerns related to complex coding scripts. The source code and a detailed tutorial for MLme are available at https://github.com/FunctionalUrology/MLme.
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spelling pubmed-103499952023-07-17 Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis Akshay, Akshay Katoch, Mitali Shekarchizadeh, Navid Abedi, Masoud Sharma, Ankush Burkhard, Fiona C. Adam, Rosalyn M. Monastyrskaya, Katia Gheinani, Ali Hashemi bioRxiv Article BACKGROUND: Machine learning (ML) has emerged as a vital asset for researchers to analyze and extract valuable information from complex datasets. However, developing an effective and robust ML pipeline can present a real challenge, demanding considerable time and effort, thereby impeding research progress. Existing tools in this landscape require a profound understanding of ML principles and programming skills. Furthermore, users are required to engage in the comprehensive configuration of their ML pipeline to obtain optimal performance. RESULTS: To address these challenges, we have developed a novel tool called Machine Learning Made Easy (MLme) that streamlines the use of ML in research, specifically focusing on classification problems at present. By integrating four essential functionalities, namely Data Exploration, AutoML, CustomML, and Visualization, MLme fulfills the diverse requirements of researchers while eliminating the need for extensive coding efforts. To demonstrate the applicability of MLme, we conducted rigorous testing on six distinct datasets, each presenting unique characteristics and challenges. Our results consistently showed promising performance across different datasets, reaffirming the versatility and effectiveness of the tool. Additionally, by utilizing MLme’s feature selection functionality, we successfully identified significant markers for CD8+ naive (BACH2), CD16+ (CD16), and CD14+ (VCAN) cell populations. CONCLUSION: MLme serves as a valuable resource for leveraging machine learning (ML) to facilitate insightful data analysis and enhance research outcomes, while alleviating concerns related to complex coding scripts. The source code and a detailed tutorial for MLme are available at https://github.com/FunctionalUrology/MLme. Cold Spring Harbor Laboratory 2023-07-04 /pmc/articles/PMC10349995/ /pubmed/37461685 http://dx.doi.org/10.1101/2023.07.04.546825 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Akshay, Akshay
Katoch, Mitali
Shekarchizadeh, Navid
Abedi, Masoud
Sharma, Ankush
Burkhard, Fiona C.
Adam, Rosalyn M.
Monastyrskaya, Katia
Gheinani, Ali Hashemi
Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title_full Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title_fullStr Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title_full_unstemmed Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title_short Machine Learning Made Easy (MLme): A Comprehensive Toolkit for Machine Learning-Driven Data Analysis
title_sort machine learning made easy (mlme): a comprehensive toolkit for machine learning-driven data analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10349995/
https://www.ncbi.nlm.nih.gov/pubmed/37461685
http://dx.doi.org/10.1101/2023.07.04.546825
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