Cargando…

Nuclear envelope assembly relies on CHMP-7 in the absence of BAF-LEM-mediated hole closure

Barrier-to-autointegration factor (BAF) is a DNA binding protein that crosslinks chromatin to assemble the nuclear envelope (NE) after mitosis. BAF also binds the Lap2b-Emerin-Man1 (LEM) domain family of NE proteins to repair interphase ruptures. The NE adaptors to ESCRTs, LEMD2-CHMP7, seal NE holes...

Descripción completa

Detalles Bibliográficos
Autores principales: Barger, Sarah R., Penfield, Lauren, Bahmanyar, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350047/
https://www.ncbi.nlm.nih.gov/pubmed/37461528
http://dx.doi.org/10.1101/2023.07.06.547980