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Nuclear envelope assembly relies on CHMP-7 in the absence of BAF-LEM-mediated hole closure
Barrier-to-autointegration factor (BAF) is a DNA binding protein that crosslinks chromatin to assemble the nuclear envelope (NE) after mitosis. BAF also binds the Lap2b-Emerin-Man1 (LEM) domain family of NE proteins to repair interphase ruptures. The NE adaptors to ESCRTs, LEMD2-CHMP7, seal NE holes...
Autores principales: | Barger, Sarah R., Penfield, Lauren, Bahmanyar, Shirin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350047/ https://www.ncbi.nlm.nih.gov/pubmed/37461528 http://dx.doi.org/10.1101/2023.07.06.547980 |
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