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Prolonged T cell – DC macro-clustering within lymph node microenvironments initiates Th2 cell differentiation in a site-specific manner

Formation of T helper 2 (Th2) responses has been attributed to low-grade T cell stimulation, yet how large-scale polyclonal Th2 responses are generated in vivo remains unclear. Here, we used quantitative imaging to investigate early Th2 differentiation within lymph nodes (LNs) following cutaneous al...

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Detalles Bibliográficos
Autores principales:	Lyons-Cohen, Miranda R., Shamskhou, Elya A., Gerner, Michael Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350056/ https://www.ncbi.nlm.nih.gov/pubmed/37461439 http://dx.doi.org/10.1101/2023.07.07.547554

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