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Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
INTRODUCTION: KDM2B encodes a JmjC domain-containing histone lysine demethylase, which functions as an oncogene in several types of tumors, including TNBC. This study was initiated to address the cancer relevance of the results of our earlier work, which had shown that overexpression of KDM2B render...
Autores principales: | Chavdoula, Evangelia, Anastas, Vollter, Ferlita, Alessandro La, Aldana, Julian, Carota, Giuseppe, Spampinato, Mariarita, Soysal, Burak, Cosentini, Ilaria, Parashar, Sameer, Sircar, Anuvrat, Nigita, Giovanni, Sehgal, Lalit, Freitas, Michael A., Tsichlis, Philip N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350079/ https://www.ncbi.nlm.nih.gov/pubmed/37461630 http://dx.doi.org/10.1101/2023.07.07.548031 |
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