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Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in Clostridioides difficile

The gut microbiome engenders colonization resistance against the diarrheal pathogen Clostridioides difficile but the molecular basis of this colonization resistance is incompletely understood. A prominent class of gut microbiome-produced metabolites important for colonization resistance against C. d...

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Detalles Bibliográficos
Autores principales:	Pensinger, Daniel A., Dobrila, Horia A., Stevenson, David M., Davis, Nicole M., Amador-Noguez, Daniel, Hryckowian, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350080/ https://www.ncbi.nlm.nih.gov/pubmed/37461482 http://dx.doi.org/10.1101/2023.07.06.548018

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