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Protein Binding Leads to Reduced Stability and Solvated Disorder in the Polystyrene Nanoparticle Corona

Understanding the conformation of proteins in the nanoparticle corona has important implications in how organisms respond to nanoparticle-based drugs. These proteins coat the nanoparticle surface, and their properties will influence the nanoparticle’s interaction with cell targets and the immune sys...

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Detalles Bibliográficos
Autores principales: Somarathne, Radha P., Amarasekara, Dhanush L., Kariyawasam, Chathuri S., Robertson, Harley A., Mayatt, Railey, Fitzkee, Nicholas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350082/
https://www.ncbi.nlm.nih.gov/pubmed/37461509
http://dx.doi.org/10.1101/2023.07.06.548033