SIRT1 Regulates Hepatocyte Programmed Cell Death via GSDME – IL18 Axis in Human and Mouse Liver Transplantation

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Sirtuin 1 (SIRT1) is a histone/protein deacetylase involved in cellular senescence, inflammation, and stress resistance. We previously reported that myeloid SIRT1 signaling regulates the inflamed liver’s canonical pyroptosis cell death pathway. However, whether/how hepatocyte SIRT1 is engaged in pro...

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Detalles Bibliográficos
Autores principales: Kadono, Kentaro, Kojima, Hidenobu, Yao, Siyuan, Kageyama, Shoichi, Nakamura, Kojiro, Hirao, Hirofumi, Ito, Takahiro, Dery, Kenneth, Farmer, Douglas, Kaldas, Fady, Li, Xiaoling, Kupiec-weglinski, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350112/
https://www.ncbi.nlm.nih.gov/pubmed/37461687
http://dx.doi.org/10.21203/rs.3.rs-2986981/v1
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