Structure-based network analysis predicts mutations associated with inherited retinal disease

With continued advances in gene sequencing technologies comes the need to develop better tools to understand which mutations cause disease. Here we validate structure-based network analysis (SBNA)(1,2) in well-studied human proteins and report results of using SBNA to identify critical amino acids t...

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Detalles Bibliográficos
Autores principales: Hauser, Blake M., Luo, Yuyang, Nathan, Anusha, Gaiha, Gaurav D., Vavvas, Demetrios, Comander, Jason, Pierce, Eric A., Place, Emily M., Bujakowska, Kinga M., Rossin, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350150/
https://www.ncbi.nlm.nih.gov/pubmed/37461650
http://dx.doi.org/10.1101/2023.07.05.23292247

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