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RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter
BACKGROUND: Megakaryocytes (MKs) are platelet precursors, which arise from hematopoietic stem cells (HSCs). While MK lineage commitment and differentiation are accompanied by changes in gene expression, many factors that modulate megakaryopoiesis remain to be uncovered. Replication origin binding pr...
Autores principales: | Jo, Jae-Hyun, Ok, Seon-Mi, Kim, Dong-Kyu, Kim, Yeong-Mu, Park, Jong-Uk, Jung, Dong-Hyun, Kim, Hye-Ji, Seong, Hyun-A, Cho, Hyo Je, Nah, Jihoon, Kim, Sangjune, Fu, Haiqing, Redon, Christophe E., Aladjem, Mirit I., Jang, Sang-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350187/ https://www.ncbi.nlm.nih.gov/pubmed/37461562 http://dx.doi.org/10.21203/rs.3.rs-3045396/v1 |
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