A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development

The novel long non-coding RNA (lncRNA) Leat1 is extraordinarily conserved in both its location (syntenic with EfnB2, an essential gene in anogenital patterning) and sequence. Here we show that Leat1 is upregulated following the testosterone surge from the developing testis and directly interacts wit...

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Detalles Bibliográficos
Autores principales: Mattiske, Deidre, Bernard, Pascal, Gradie, Paul E., Behringer, Richard R., Overbeek, Paul A., O’Neill, Rachel J, Phillips, Tiffany, Tarulli, Gerard, Pask, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350214/
https://www.ncbi.nlm.nih.gov/pubmed/37461443
http://dx.doi.org/10.21203/rs.3.rs-3098271/v1

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