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Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use

BACKGROUND: Disinfectant towelettes are increasingly being used as a means to prevent transmission of clinically important pathogens which could lead to healthcare-associated infections (HAIs). However, the efficacy of disinfectant towelette products when tested under realistic use conditions is und...

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Autores principales: Kelley, Alyssa M., Voorn, Maxwell G., Tembo, Geraldine M., Horn, Connor M., Li, Xiaobao, Teska, Peter J., Oliver, Haley F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350269/
https://www.ncbi.nlm.nih.gov/pubmed/37455322
http://dx.doi.org/10.1186/s13756-023-01266-4
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author Kelley, Alyssa M.
Voorn, Maxwell G.
Tembo, Geraldine M.
Horn, Connor M.
Li, Xiaobao
Teska, Peter J.
Oliver, Haley F.
author_facet Kelley, Alyssa M.
Voorn, Maxwell G.
Tembo, Geraldine M.
Horn, Connor M.
Li, Xiaobao
Teska, Peter J.
Oliver, Haley F.
author_sort Kelley, Alyssa M.
collection PubMed
description BACKGROUND: Disinfectant towelettes are increasingly being used as a means to prevent transmission of clinically important pathogens which could lead to healthcare-associated infections (HAIs). However, the efficacy of disinfectant towelette products when tested under realistic use conditions is understudied. A test model was designed to replicate realistic wiping conditions. The objective of this study was to determine the impact of varied contact time on disinfectant towelette efficacy under these conditions. METHODS: Five product types were tested against Staphylococcus aureus (ATCC 6538) and Pseudomonas aeruginosa (ATCC 15,442) at five contact times (30 s, one min, two min, three min, and 10 min) on hard, non-porous laminate templates to determine the impact of contact time on disinfectant towelette efficacy when tested under realistic use. RESULTS: Product type had a significant impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use. The effect of contact time was limited and no differences in efficacy were seen at a contact time of one min compared with the other contact times tested. Only one disinfectant towelette product achieved a mean 5-log reduction under the tested conditions. CONCLUSION: Efficacy of disinfectant towelettes was primarily impacted by product type when applied in a model designed to replicate realistic use in which only a limited effect of contact time was observed. There is a need for further investigation into which factors have the greatest impact on disinfectant towelette efficacy when applied in clinical settings.
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spelling pubmed-103502692023-07-17 Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use Kelley, Alyssa M. Voorn, Maxwell G. Tembo, Geraldine M. Horn, Connor M. Li, Xiaobao Teska, Peter J. Oliver, Haley F. Antimicrob Resist Infect Control Research BACKGROUND: Disinfectant towelettes are increasingly being used as a means to prevent transmission of clinically important pathogens which could lead to healthcare-associated infections (HAIs). However, the efficacy of disinfectant towelette products when tested under realistic use conditions is understudied. A test model was designed to replicate realistic wiping conditions. The objective of this study was to determine the impact of varied contact time on disinfectant towelette efficacy under these conditions. METHODS: Five product types were tested against Staphylococcus aureus (ATCC 6538) and Pseudomonas aeruginosa (ATCC 15,442) at five contact times (30 s, one min, two min, three min, and 10 min) on hard, non-porous laminate templates to determine the impact of contact time on disinfectant towelette efficacy when tested under realistic use. RESULTS: Product type had a significant impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use. The effect of contact time was limited and no differences in efficacy were seen at a contact time of one min compared with the other contact times tested. Only one disinfectant towelette product achieved a mean 5-log reduction under the tested conditions. CONCLUSION: Efficacy of disinfectant towelettes was primarily impacted by product type when applied in a model designed to replicate realistic use in which only a limited effect of contact time was observed. There is a need for further investigation into which factors have the greatest impact on disinfectant towelette efficacy when applied in clinical settings. BioMed Central 2023-07-16 /pmc/articles/PMC10350269/ /pubmed/37455322 http://dx.doi.org/10.1186/s13756-023-01266-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kelley, Alyssa M.
Voorn, Maxwell G.
Tembo, Geraldine M.
Horn, Connor M.
Li, Xiaobao
Teska, Peter J.
Oliver, Haley F.
Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title_full Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title_fullStr Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title_full_unstemmed Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title_short Contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
title_sort contact time has limited impact on the efficacy of disinfectant towelettes when tested under conditions reflective of realistic use
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350269/
https://www.ncbi.nlm.nih.gov/pubmed/37455322
http://dx.doi.org/10.1186/s13756-023-01266-4
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