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Infection Masquerading As Spontaneous Tumor Lysis Syndrome

Tumor lysis syndrome (TLS) is a life-threatening condition due to malignant tumor cell lysis resulting in severe metabolic derangements that require prompt recognition and management to prevent progression to end-organ damage and death. This case describes a patient presenting with clinical and labo...

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Detalles Bibliográficos
Autores principales: DeSalvo, Jen, Rossetti, Allison L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350283/
https://www.ncbi.nlm.nih.gov/pubmed/37461769
http://dx.doi.org/10.7759/cureus.40503
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author DeSalvo, Jen
Rossetti, Allison L
author_facet DeSalvo, Jen
Rossetti, Allison L
author_sort DeSalvo, Jen
collection PubMed
description Tumor lysis syndrome (TLS) is a life-threatening condition due to malignant tumor cell lysis resulting in severe metabolic derangements that require prompt recognition and management to prevent progression to end-organ damage and death. This case describes a patient presenting with clinical and laboratory abnormalities complicated by multi-organ dysfunction concerning spontaneous TLS from a suspected undiagnosed malignancy. The patient had an unremarkable malignancy workup and was ultimately diagnosed with endocarditis, which improved with treatment of the infection. Therefore, this case demonstrates that systemic infections may rarely present with metabolic abnormalities and multi-organ dysfunction resembling spontaneous TLS.
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spelling pubmed-103502832023-07-17 Infection Masquerading As Spontaneous Tumor Lysis Syndrome DeSalvo, Jen Rossetti, Allison L Cureus Internal Medicine Tumor lysis syndrome (TLS) is a life-threatening condition due to malignant tumor cell lysis resulting in severe metabolic derangements that require prompt recognition and management to prevent progression to end-organ damage and death. This case describes a patient presenting with clinical and laboratory abnormalities complicated by multi-organ dysfunction concerning spontaneous TLS from a suspected undiagnosed malignancy. The patient had an unremarkable malignancy workup and was ultimately diagnosed with endocarditis, which improved with treatment of the infection. Therefore, this case demonstrates that systemic infections may rarely present with metabolic abnormalities and multi-organ dysfunction resembling spontaneous TLS. Cureus 2023-06-16 /pmc/articles/PMC10350283/ /pubmed/37461769 http://dx.doi.org/10.7759/cureus.40503 Text en Copyright © 2023, DeSalvo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
DeSalvo, Jen
Rossetti, Allison L
Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title_full Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title_fullStr Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title_full_unstemmed Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title_short Infection Masquerading As Spontaneous Tumor Lysis Syndrome
title_sort infection masquerading as spontaneous tumor lysis syndrome
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350283/
https://www.ncbi.nlm.nih.gov/pubmed/37461769
http://dx.doi.org/10.7759/cureus.40503
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