Cargando…

Stratification of diabetes in the context of comorbidities, using representation learning and topological data analysis

Diabetes is a heterogenous, multimorbid disorder with a large variation in manifestations, trajectories, and outcomes. The aim of this study is to validate a novel machine learning method for the phenotyping of diabetes in the context of comorbidities. Data from 9967 multimorbid patients with a new...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wamil, Malgorzata, Hassaine, Abdelaali, Rao, Shishir, Li, Yikuan, Mamouei, Mohammad, Canoy, Dexter, Nazarzadeh, Milad, Bidel, Zeinab, Copland, Emma, Rahimi, Kazem, Salimi-Khorshidi, Gholamreza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350454/ https://www.ncbi.nlm.nih.gov/pubmed/37455284 http://dx.doi.org/10.1038/s41598-023-38251-1

Ejemplares similares

Systolic Blood Pressure and Cardiovascular Risk in Patients With Diabetes: A Prospective Cohort Study
por: Rao, Shishir, et al.
Publicado: (2022)

Hi-BEHRT: Hierarchical Transformer-Based Model for Accurate Prediction of Clinical Events Using Multimodal Longitudinal Electronic Health Records
por: Li, Yikuan, et al.
Publicado: (2023)

Validation of risk prediction models applied to longitudinal electronic health record data for the prediction of major cardiovascular events in the presence of data shifts
por: Li, Yikuan, et al.
Publicado: (2022)

Systolic blood pressure, chronic obstructive pulmonary disease and cardiovascular risk
por: Rao, Shishir, et al.
Publicado: (2023)

Publisher Correction: Deep Bayesian Gaussian processes for uncertainty estimation in electronic health records
por: Li, Yikuan, et al.
Publicado: (2021)

Deep Bayesian Gaussian processes for uncertainty estimation in electronic health records
por: Li, Yikuan, et al.
Publicado: (2021)

Untangling the complexity of multimorbidity with machine learning
por: Hassaine, Abdelaali, et al.
Publicado: (2020)

Investigating the association of environmental exposures and all-cause mortality in the UK Biobank using sparse principal component analysis
por: Mamouei, Mohammad, et al.
Publicado: (2022)

How Much Lowering of Blood Pressure Is Required to Prevent Cardiovascular Disease in Patients With and Without Previous Cardiovascular Disease?
por: Canoy, Dexter, et al.
Publicado: (2022)

Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study
por: Nazarzadeh, Milad, et al.
Publicado: (2020)

BEHRT: Transformer for Electronic Health Records
por: Li, Yikuan, et al.
Publicado: (2020)

Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices
por: Canoy, Dexter, et al.
Publicado: (2021)

Sodium-based paracetamol: impact on blood pressure, cardiovascular events, and all-cause mortality
por: Rao, Shishir, et al.
Publicado: (2023)

Blood pressure and risk of venous thromboembolism: a cohort analysis of 5.5 million UK adults and Mendelian randomization studies
por: Nazarzadeh, Milad, et al.
Publicado: (2022)

Long‐Term Exposure to Elevated Systolic Blood Pressure in Predicting Incident Cardiovascular Disease: Evidence From Large‐Scale Routine Electronic Health Records
por: Ayala Solares, Jose Roberto, et al.
Publicado: (2019)

A comparative study of model-centric and data-centric approaches in the development of cardiovascular disease risk prediction models in the UK Biobank
por: Mamouei, Mohammad, et al.
Publicado: (2023)

Predicting the risk of emergency admission with machine learning: Development and validation using linked electronic health records
por: Rahimian, Fatemeh, et al.
Publicado: (2018)

Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC)
por: Rahimi, Kazem, et al.
Publicado: (2019)

Multi-morbidity and blood pressure trajectories in hypertensive patients: A multiple landmark cohort study
por: Tran, Jenny, et al.
Publicado: (2021)

Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis
por: Nazarzadeh, Milad, et al.
Publicado: (2021)

Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis
por: Copland, Emma, et al.
Publicado: (2021)

Genetic susceptibility, elevated blood pressure, and risk of atrial fibrillation: a Mendelian randomization study
por: Nazarzadeh, Milad, et al.
Publicado: (2021)

Patterns and temporal trends of comorbidity among adult patients with incident cardiovascular disease in the UK between 2000 and 2014: A population-based cohort study
por: Tran, Jenny, et al.
Publicado: (2018)

Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients
por: Conrad, Nathalie, et al.
Publicado: (2019)

Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis
por: Nazarzadeh, Milad, et al.
Publicado: (2022)

Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials
por: Canoy, Dexter, et al.
Publicado: (2022)

Temporal Trends and Patterns in Mortality After Incident Heart Failure: A Longitudinal Analysis of 86 000 Individuals
por: Conrad, Nathalie, et al.
Publicado: (2019)

Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis
por: Pinho-Gomes, Ana-Catarina, et al.
Publicado: (2021)

Determination of the social related factors of suicide in Iran: a systematic review and meta-analysis
por: Nazarzadeh, Milad, et al.
Publicado: (2013)

Usual blood pressure, atrial fibrillation and vascular risk: evidence from 4.3 million adults
por: Emdin, Connor A, et al.
Publicado: (2017)

Usual blood pressure, peripheral arterial disease, and vascular risk: cohort study of 4.2 million adults
por: Emdin, Connor A, et al.
Publicado: (2015)

Self-reported and objectively measured physical activity in people with and without chronic heart failure: UK Biobank analysis
por: O'Donnell, Johanna, et al.
Publicado: (2020)

Ambient Air Pollution and Respiratory Health in Sub-Saharan African Children: A Cross-Sectional Analysis
por: Cai, Yutong Samuel, et al.
Publicado: (2021)

Elevated blood pressure and risk of mitral regurgitation: A longitudinal cohort study of 5.5 million United Kingdom adults
por: Rahimi, Kazem, et al.
Publicado: (2017)

Editorial: Hypertension During Pregnancy and Future Risk of Cardiovascular and Other Long-Term Health Outcomes
por: Henry, Amanda, et al.
Publicado: (2020)

The effect of immunomodulatory drugs on aortic stenosis: a Mendelian randomisation analysis
por: Ciofani, Jonathan L., et al.
Publicado: (2023)

Elevated blood pressure, antihypertensive medications and bone health in the population: revisiting old hypotheses and exploring future research directions
por: Canoy, D., et al.
Publicado: (2021)

Correction: Elevated blood pressure, antihypertensive medications and bone health in the population: revisiting old hypotheses and exploring future research directions
por: Canoy, D., et al.
Publicado: (2022)

Editorial: Renal function and related biomarkers in cardiovascular risk assessment and prevention
por: Lin, Gen-Min, et al.
Publicado: (2022)

An interpretable machine learning framework for measuring urban perceptions from panoramic street view images
por: Liu, Yunzhe, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_00h6c19ovk6106agb75ifbe4qo