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Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model

BACKGROUND: Antimicrobial stewardship (AMS) is imperative in addressing the menace of antimicrobial resistance (AMR) in health systems. Commonwealth Partnerships for Antimicrobial Stewardship uses a health partnership model to establish AMS in Commonwealth countries. The Hospital of Kwame Nkrumah Un...

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Autores principales: Amponsah, Obed Kwabena Offe, Courtenay, Aaron, Ayisi-Boateng, Nana Kwame, Abuelhana, Ahmed, Opoku, Douglas Aninng, Blay, Lawrence Kobina, Abruquah, Nana Akua, Osafo, Annabella Bensusan, Danquah, Charlotte Boachie, Tawiah, Phyllis, Opare-Addo, Mercy Naa Aduele, Owusu-Ofori, Alex, Buabeng, Kwame Ohene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350667/
https://www.ncbi.nlm.nih.gov/pubmed/37465105
http://dx.doi.org/10.1093/jacamr/dlad084
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author Amponsah, Obed Kwabena Offe
Courtenay, Aaron
Ayisi-Boateng, Nana Kwame
Abuelhana, Ahmed
Opoku, Douglas Aninng
Blay, Lawrence Kobina
Abruquah, Nana Akua
Osafo, Annabella Bensusan
Danquah, Charlotte Boachie
Tawiah, Phyllis
Opare-Addo, Mercy Naa Aduele
Owusu-Ofori, Alex
Buabeng, Kwame Ohene
author_facet Amponsah, Obed Kwabena Offe
Courtenay, Aaron
Ayisi-Boateng, Nana Kwame
Abuelhana, Ahmed
Opoku, Douglas Aninng
Blay, Lawrence Kobina
Abruquah, Nana Akua
Osafo, Annabella Bensusan
Danquah, Charlotte Boachie
Tawiah, Phyllis
Opare-Addo, Mercy Naa Aduele
Owusu-Ofori, Alex
Buabeng, Kwame Ohene
author_sort Amponsah, Obed Kwabena Offe
collection PubMed
description BACKGROUND: Antimicrobial stewardship (AMS) is imperative in addressing the menace of antimicrobial resistance (AMR) in health systems. Commonwealth Partnerships for Antimicrobial Stewardship uses a health partnership model to establish AMS in Commonwealth countries. The Hospital of Kwame Nkrumah University of Science and Technology in partnership with Ulster University, Northern Ireland, undertook an AMS project from November 2021 to May 2022. We report on implementation of the AMS, its impact on antibiotic use and infections management at the University Hospital; Kumasi, Ghana. METHODS: The Global-Point Prevalence Survey (PPS) protocol was used to assess antibiotics use at the hospital at baseline, midpoint and end of the project. Feedback on each PPS was given to the hospital to inform practice, behavioural change and improve antibiotic use. RESULTS: Antibiotic use reduced from 65% at baseline to 59.7% at the end of the project. The rate of healthcare-associated infections also reduced from 17.5% at baseline to 6.5%. Use of antibiotics from the WHO Access group was 40% at baseline but increased to 50% at the endpoint. Watch antibiotics reduced from 60% to 50% from baseline. Culture and susceptibility requests increased from baseline of 111 total requests to 330 requests in the intervention period to inform antimicrobial therapy CONCLUSION: The model AMS instituted improved antibiotic use and quality of antimicrobial therapy within the study period. Continuous staff education and training in AMS, and use of standard tools for assessment and application of local data to inform infections management will ensure sustenance and improvement in the gains made.
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spelling pubmed-103506672023-07-18 Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model Amponsah, Obed Kwabena Offe Courtenay, Aaron Ayisi-Boateng, Nana Kwame Abuelhana, Ahmed Opoku, Douglas Aninng Blay, Lawrence Kobina Abruquah, Nana Akua Osafo, Annabella Bensusan Danquah, Charlotte Boachie Tawiah, Phyllis Opare-Addo, Mercy Naa Aduele Owusu-Ofori, Alex Buabeng, Kwame Ohene JAC Antimicrob Resist Original Article BACKGROUND: Antimicrobial stewardship (AMS) is imperative in addressing the menace of antimicrobial resistance (AMR) in health systems. Commonwealth Partnerships for Antimicrobial Stewardship uses a health partnership model to establish AMS in Commonwealth countries. The Hospital of Kwame Nkrumah University of Science and Technology in partnership with Ulster University, Northern Ireland, undertook an AMS project from November 2021 to May 2022. We report on implementation of the AMS, its impact on antibiotic use and infections management at the University Hospital; Kumasi, Ghana. METHODS: The Global-Point Prevalence Survey (PPS) protocol was used to assess antibiotics use at the hospital at baseline, midpoint and end of the project. Feedback on each PPS was given to the hospital to inform practice, behavioural change and improve antibiotic use. RESULTS: Antibiotic use reduced from 65% at baseline to 59.7% at the end of the project. The rate of healthcare-associated infections also reduced from 17.5% at baseline to 6.5%. Use of antibiotics from the WHO Access group was 40% at baseline but increased to 50% at the endpoint. Watch antibiotics reduced from 60% to 50% from baseline. Culture and susceptibility requests increased from baseline of 111 total requests to 330 requests in the intervention period to inform antimicrobial therapy CONCLUSION: The model AMS instituted improved antibiotic use and quality of antimicrobial therapy within the study period. Continuous staff education and training in AMS, and use of standard tools for assessment and application of local data to inform infections management will ensure sustenance and improvement in the gains made. Oxford University Press 2023-07-17 /pmc/articles/PMC10350667/ /pubmed/37465105 http://dx.doi.org/10.1093/jacamr/dlad084 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Amponsah, Obed Kwabena Offe
Courtenay, Aaron
Ayisi-Boateng, Nana Kwame
Abuelhana, Ahmed
Opoku, Douglas Aninng
Blay, Lawrence Kobina
Abruquah, Nana Akua
Osafo, Annabella Bensusan
Danquah, Charlotte Boachie
Tawiah, Phyllis
Opare-Addo, Mercy Naa Aduele
Owusu-Ofori, Alex
Buabeng, Kwame Ohene
Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title_full Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title_fullStr Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title_full_unstemmed Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title_short Assessing the impact of antimicrobial stewardship implementation at a district hospital in Ghana using a health partnership model
title_sort assessing the impact of antimicrobial stewardship implementation at a district hospital in ghana using a health partnership model
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350667/
https://www.ncbi.nlm.nih.gov/pubmed/37465105
http://dx.doi.org/10.1093/jacamr/dlad084
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