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Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis

BACKGROUND: The long-term efficacy of the Dumon stent in the treatment of benign airway stenosis is unclear. OBJECTIVE: The objective of this study was to evaluate the long-term efficacy and safety of the Dumon stent in patients with benign airway stenosis. METHODS: We retrospectively reviewed patie...

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Autores principales: Lin, Li-Qin, Chen, Di-Fei, Wu, Hong-Kai, Chen, Yu, Zhong, Chang-Hao, Chen, Xiao-Bo, Tang, Chun-Li, Zhou, Zi-Qing, Li, Shi-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350742/
https://www.ncbi.nlm.nih.gov/pubmed/37439480
http://dx.doi.org/10.1177/17534666231181269
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author Lin, Li-Qin
Chen, Di-Fei
Wu, Hong-Kai
Chen, Yu
Zhong, Chang-Hao
Chen, Xiao-Bo
Tang, Chun-Li
Zhou, Zi-Qing
Li, Shi-Yue
author_facet Lin, Li-Qin
Chen, Di-Fei
Wu, Hong-Kai
Chen, Yu
Zhong, Chang-Hao
Chen, Xiao-Bo
Tang, Chun-Li
Zhou, Zi-Qing
Li, Shi-Yue
author_sort Lin, Li-Qin
collection PubMed
description BACKGROUND: The long-term efficacy of the Dumon stent in the treatment of benign airway stenosis is unclear. OBJECTIVE: The objective of this study was to evaluate the long-term efficacy and safety of the Dumon stent in patients with benign airway stenosis. METHODS: We retrospectively reviewed patients with benign airway stenosis who were treated with a Dumon stent at the First Affiliated Hospital of Guangzhou Medical University between March 2014 and October 2021. We included patients with successful removal of silicone stents after implantation. The clinical data and information on bronchoscopic interventional procedures and related complications were collected and analyzed. RESULTS: Ninety-nine patients with benign airway stenosis were included. The stent was placed mainly in the trachea (44.4%) and left main bronchus (43.4%). The main type of stenosis was post-tuberculosis bronchial stenosis (57.6%). The overall cure rate was 60.6%. Stent-related complications included retention of secretions (70.7%), granuloma formation (67.7%), stent angulation (21.2%), and stent migration (12.1%). The stent was less effective for left main bronchus stenosis (p = 0.012). Multivariate logistic regression analysis identified that stent placement for more than 13 months, a stent-intervention number of ⩽ 1 predicted a favorable outcome. CONCLUSION: The efficacy and safety of the Dumon stent for benign airway stenosis need improvement. The stent is less effective for left main bronchus stenosis; regular follow-up is required in such cases. Stent placement for > 13 months and no more than once stent intervention within a 6-month period were associated with a favorable outcome.
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spelling pubmed-103507422023-07-18 Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis Lin, Li-Qin Chen, Di-Fei Wu, Hong-Kai Chen, Yu Zhong, Chang-Hao Chen, Xiao-Bo Tang, Chun-Li Zhou, Zi-Qing Li, Shi-Yue Ther Adv Respir Dis Original Research BACKGROUND: The long-term efficacy of the Dumon stent in the treatment of benign airway stenosis is unclear. OBJECTIVE: The objective of this study was to evaluate the long-term efficacy and safety of the Dumon stent in patients with benign airway stenosis. METHODS: We retrospectively reviewed patients with benign airway stenosis who were treated with a Dumon stent at the First Affiliated Hospital of Guangzhou Medical University between March 2014 and October 2021. We included patients with successful removal of silicone stents after implantation. The clinical data and information on bronchoscopic interventional procedures and related complications were collected and analyzed. RESULTS: Ninety-nine patients with benign airway stenosis were included. The stent was placed mainly in the trachea (44.4%) and left main bronchus (43.4%). The main type of stenosis was post-tuberculosis bronchial stenosis (57.6%). The overall cure rate was 60.6%. Stent-related complications included retention of secretions (70.7%), granuloma formation (67.7%), stent angulation (21.2%), and stent migration (12.1%). The stent was less effective for left main bronchus stenosis (p = 0.012). Multivariate logistic regression analysis identified that stent placement for more than 13 months, a stent-intervention number of ⩽ 1 predicted a favorable outcome. CONCLUSION: The efficacy and safety of the Dumon stent for benign airway stenosis need improvement. The stent is less effective for left main bronchus stenosis; regular follow-up is required in such cases. Stent placement for > 13 months and no more than once stent intervention within a 6-month period were associated with a favorable outcome. SAGE Publications 2023-07-13 /pmc/articles/PMC10350742/ /pubmed/37439480 http://dx.doi.org/10.1177/17534666231181269 Text en © The Author(s), 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Lin, Li-Qin
Chen, Di-Fei
Wu, Hong-Kai
Chen, Yu
Zhong, Chang-Hao
Chen, Xiao-Bo
Tang, Chun-Li
Zhou, Zi-Qing
Li, Shi-Yue
Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title_full Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title_fullStr Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title_full_unstemmed Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title_short Long-term efficacy and safety of the Dumon stent for treatment of benign airway stenosis
title_sort long-term efficacy and safety of the dumon stent for treatment of benign airway stenosis
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350742/
https://www.ncbi.nlm.nih.gov/pubmed/37439480
http://dx.doi.org/10.1177/17534666231181269
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