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Ebselen: A promising therapy protecting cardiomyocytes from excess iron in iron-overloaded thalassemia patients

Iron-overload-associated cardiomyopathy has been one of the primary causes of mortality in thalassemia patients with iron burden. There is growing evidence citing the beneficial effects of ebselen as an antioxidant selectively blocking the divalent metal transporter 1 (DMT-1) to deter iron ingress i...

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Detalles Bibliográficos
Autores principales: Ghazaiean, Mobin, Aliasgharian, Aily, Karami, Hossein, Darvishi-Khezri, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350894/
https://www.ncbi.nlm.nih.gov/pubmed/37465348
http://dx.doi.org/10.1515/med-2023-0733