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Ebselen: A promising therapy protecting cardiomyocytes from excess iron in iron-overloaded thalassemia patients
Iron-overload-associated cardiomyopathy has been one of the primary causes of mortality in thalassemia patients with iron burden. There is growing evidence citing the beneficial effects of ebselen as an antioxidant selectively blocking the divalent metal transporter 1 (DMT-1) to deter iron ingress i...
Autores principales: | Ghazaiean, Mobin, Aliasgharian, Aily, Karami, Hossein, Darvishi-Khezri, Hadi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350894/ https://www.ncbi.nlm.nih.gov/pubmed/37465348 http://dx.doi.org/10.1515/med-2023-0733 |
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