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Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant Enterococcus

[Image: see text] The continued efficacy of glycopeptide antibiotics (GPAs) against Gram-positive bacteria is challenged by the emergence and spread of GPA-resistant pathogens, particularly vancomycin-resistant enterococci (VRE). The growing frequency of GPA resistance propels the need for innovativ...

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Detalles Bibliográficos
Autores principales:	Koteva, Kalinka, Xu, Min, Wang, Wenliang, Fiebig-Comyn, Aline A., Cook, Michael A., Coombes, Brian K., Wright, Gerard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350919/ https://www.ncbi.nlm.nih.gov/pubmed/37315221 http://dx.doi.org/10.1021/acs.jmedchem.3c00633

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