Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

[Image: see text] Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine and essential signaling protein associated with inflammation and cancers. One of the newly described roles of MIF is binding to apoptosis-inducing factor (AIF) that “brings” cells to death in pathological co...

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Detalles Bibliográficos
Autores principales: Chen, Deng, Osipyan, Angelina, Adriana, Jeaunice, Kader, Mohammed, Gureev, Maxim, Knol, Catharina W. J., Sigmund, Marie-Cathérine, Xiao, Zhangping, van der Wouden, Petra E., Cool, Robbert H., Poelarends, Gerrit J., Dekker, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350922/
https://www.ncbi.nlm.nih.gov/pubmed/37352470
http://dx.doi.org/10.1021/acs.jmedchem.3c00397

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